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Search Results for " peroxisome proliferator-activated receptor gamma "
Targets Recommended: PPAR

15

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T8780 AMG131

INT-131,AMG-131,CHS 131

PPAR DNA Damage/DNA Repair; Metabolism
AMG131 (CHS 131) 是一种新型非噻唑烷二酮(TZD) 选择性过氧化物酶体增殖物激活受体 (PPAR) γ 调节剂,可用于治疗 2 型糖尿病。
T0371 Gliquidone

AR-DF 26,格列喹酮,Glurenorm

Potassium Channel Membrane transporter/Ion channel
Gliquidone (AR-DF 26) 是一种磺酰脲类的抗糖尿病药物,可用于2型糖尿病的研究。
T69146 Suksdorfin

PPAR DNA Damage/DNA Repair; Metabolism
Suksdorfin 具有降血糖作用,可促进脂肪细胞分化并增强脂联素的产生,可激活过氧化物酶体增殖物激活受体 γ (PPARγ),可促进脂肪细胞对胰岛素依赖性葡萄糖的摄取,可用于肥胖相关研究。
T69635 NIP-222

NIP-222 is a peroxisome proliferator-activated receptor (PPAR)gamma agonist.
T69191 Pemaglitazar

Pemaglitazar is a dual peroxisome proliferator-activated receptor (PPAR) alpha and gamma agonist, with hypoglycemic activity.
T27324 FK614

FK 614,ATx-08-001,ATx-08001,FK-614

FK-614 is a selective agonist of peroxisome proliferator-activated receptor gamma. FK-614 improves peripheral glucose utilization while decreases hepatic insulin extraction in alloxan-induced diabetic dogs.
T68000 MK 0533

Mk-0533是一种选择性过氧化物酶体增殖激活受体γ调节剂,用于治疗2型糖尿病。
T73519 FX-909

FX-909 是一种共价过氧化物酶体增殖体激活受体 γ (PPARG) 逆激动剂。FX-909 可用于肿瘤的研究。
T61417 PPARγ agonist 7

PPARγ agonist 7 (Compound 3a) is a highly potent and selective agonist of the peroxisome proliferator-activated receptor gamma (PPARγ). It specifically stimulates adiponectin production in human bone marrow mesenchymal stem cells (hBM-MSCs), making it an innovative full agonist of PPARγ with an EC 50 value of 4.34 μM [1].
T79182 PPARγ agonist 8

PPAR DNA Damage/DNA Repair; Metabolism
PPARγ agonist8,作为PPARγ的激动剂,能够诱导过氧化物酶体增殖反应元件(PPRE)-萤光素酶活性,其EC50值为0.2 μM。
T61836 Pioglitazone potassium

Pioglitazone potassium (U 72107) is an orally active and selective agonist of peroxisome proliferator-activated receptor gamma (PPARγ). It demonstrates high affinity binding to the ligand-binding domain of PPARγ, with an EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. Pioglitazone potassium has applications in diabetes research [2] [3] [4].
T13483 RP 54275

2-Octadecyl-1H-indole-5-carboxylic acid

Others Others
RP 54275 是一种天然存在的脂肪酸衍生物,一种新的降胆固醇化合物。它可以激活过氧化物酶体增殖物激活受体γ(PPARγ)途径,该途径参与脂质代谢、炎症和细胞分化的调节。
T75009 PPARγ/GR modulator 1

PPARγ/GR modulator 1 是一种口服活性的 PPARγ和糖皮质激素受体 (GR) 的双动激动剂,Ki 值分别为 3.3 和 33.6 μM。PPARγ/GR modulator 1 可用于研究代谢疾病,例如糖尿病。
T79284 IR-251

IR-251是一种线粒体靶向的近红外荧光探针,通过OATP导向线粒体,诱导肿瘤细胞中线粒体损伤。IR-251抑制PPARγ,从而引发ROS的过量生成,进而抑制β-catenin信号通路及相关细胞周期和转移的下游蛋白,有效抑止肿瘤的增殖和转移。
T65598 Cefminox sodium

Cefminox (Sodium) is a new cephamycin antibiotic possessing a D-amino acid moiety derived from D-cysteine at the C-7B side chain. Cefminox is active against a wide range of bacteria, especially Gram-negative and anaerobic bacteria. Cefminox shows excellent in vivo efficacy (ED50) which is higher than would be expected from its in vitro activity (MIC). Moreover, cefminox possesses more potent activity in suppression of bacterial regrowth than other cephems[1]. Cefminox (Sodium) was the most activ...

化合物

AMG131
Cat.No: T8780
Synonym: INT-131,AMG-131,CHS 131
Target: PPAR
Gliquidone
Cat.No: T0371
Synonym: AR-DF 26,格列喹酮,Glurenorm
Target: Potassium Channel
Suksdorfin
Cat.No: T69146
Synonym:
Target: PPAR
NIP-222
Cat.No: T69635
Synonym:
Target:
Pemaglitazar
Cat.No: T69191
Synonym:
Target:
FK614
Cat.No: T27324
Synonym: FK 614,ATx-08-001,ATx-08001,FK-614
Target:
MK 0533
Cat.No: T68000
Synonym:
Target:
FX-909
Cat.No: T73519
Synonym:
Target:
PPARγ agonist 7
Cat.No: T61417
Synonym:
Target:
PPARγ agonist 8
Cat.No: T79182
Synonym:
Target: PPAR
Pioglitazone potassium
Cat.No: T61836
Synonym:
Target:
RP 54275
Cat.No: T13483
Synonym: 2-Octadecyl-1H-indole-5-carboxylic acid
Target: Others
PPARγ/GR modulator 1
Cat.No: T75009
Synonym:
Target:
IR-251
Cat.No: T79284
Synonym:
Target:
Cefminox sodium
Cat.No: T65598
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-02575 PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)

CIMT1,PPARγ,GLM1,PPARgamma,PPARG1,PPARG2,NR1C3,...

Human Baculovirus Insect Cells
Peroxisome proliferator-activated receptor gamma (PPARG), a nuclear hormone receptor, plays a critical role in the lipid and glucose homeostasis, adipocyte differentiation, as well as intracellular insulin-signaling events. The peroxisome proliferator-activated receptor gamma (PPARgamma) regulates osteoblast and osteoclast differentiation, and is the molecular target of thiazolidinediones (TZDs), insulin sensitizers that enhance glucose utilization and adipocyte differentiation. Peroxisome proli...
TMPJ-01213 ASXL1 Protein, Human, Recombinant (GST)

Putative Polycomb group protein ASXL1,Additional sex combs-l...

Human E. coli
Putative Polycomb group protein ASXL1 involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). It acts as coactivator of RARA and RXRA through association with NCOA1. ASXL1 also acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 t...
TMPJ-00705 BCAS2 Protein, Human, Recombinant (His, T7)

BCAS2,DNA Amplified in Mammary Carcinoma 1 Protein,Pre-mRNA-...

Human E. coli
Breast Carcinoma-Amplified Sequence 2 (BCAS2) is a member of the SPF27 family. BCAS2 is a nuclear protein and widely expressed in many rtissues. BCAS2 is identified as being overexpressed in various breast cancer cell lines. BCAS2 is a component of the spliceosome, taking part in the removal of introns from mRNA precursors. BCAS2 interacts with estrogen receptor alpha and beta, thyroid hormone receptor beta, peroxisome proliferator-activated receptor gamma. BCAS2 functions as an ER co-activator ...

重组蛋白

PPAR gamma/PPARG Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02575
Species: Human
Expression System: Baculovirus Insect Cells
ASXL1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01213
Species: Human
Expression System: E. coli
BCAS2 Protein, Human, Recombinant (His, T7)
Cat.No: TMPJ-00705
Species: Human
Expression System: E. coli
TargetMol Loading
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